DEMUSE© is a commercially available Matlab program for visualization and decomposition of multichannel surface electromyograms (EMG) by using the CKC technique.

Price and quotations

Originally developed within the framework of multiple European projects, DEMUSE is provided strictly as a research tool. It is not designed, intended, or certified for medical purposes, clinical decision-making, or diagnostic conclusions. As such, it is exempt from the requirements of Regulation (EU) 2017/745 of the European Parliament and of the Council on medical devices.

Key features and capabilities include:

  • load and visualize the multichannel surface electromyograms (any file format can be supported by writing a simple Matlab script that loads the signals into the DEMUSE programme),
  • decompose surface EMG signals by CKC technique into contributions of individual motor units,
  • assess the accuracy of discharge identification in each detected motor unit,
  • manually inspect and edit the results obtained by automatic decomposition,
  • display graphs of decomposition results, including plots of motor unit discharge patterns, instantaneous motor unit discharge rate, motor unit action potentials (MUAPs) and their 3D animations,
  • compare the original surface EMG signals to the reconstructed MUAP trains,
  • save and reload the decomposition results.

DEMUSE tool can be applied to high-density surface EMG signals detected by any detection system supporting at least 64 channel acquisition. The tool has been thoroughly tested and validated on the signals acquired by:

  • W-EMG portable amplifier (Laboratory for Engineering of the Neuromuscular System (LISiN) Politecnico di Torino, Italy),
  • EMG USB2 amplifier (OT Bioeletronica s.n.c., Torino, Italy).

Partners

System Software Laboratory,
Faculty of Electrical Engineering and Computer Science,
University of Maribor,
Slovenia

Contact person: prof. dr. Aleš Holobar
Website: lspo.feri.um.si

Laboratory of Engineering of Neuromuscular System and Motor Rehabilitation,
Department of Electronics,
Politecnico di Torino,
Torino, Italy

Contact person: prof. dr. Roberto Merletti
Website: www.lisin.polito.it

Neurorehabilitation Engineering Department of Bioengineering,
Imperial College London,
London, UK

Contact person: prof. dr. Dario Farina
Website: www.imperial.ac.uk/bioengineering/

Neuromuscular Research Laboratory,
Division of Endocrinology, Diabetology and Metabolism,
Department of Medical Sciences, University of Turin,
Torino, Italy

Contact person: Marco A. Minetto, MD, PhD
Website: www.unito.it/dsm

Acknowledgements

The development and validation of the DEMUSE software was supported by:

  • Slovenian Research Agency (research core funding no. P2-0041 and the project J2-7357 “Exact quantification of muscle control strategies and co-activation patterns in robot-assisted rehabilitation of hemiparetic patients”),

  • The Commission of the European Union, within Framework 6, under Grant Agreement Number 023537 “DEMUSE”; (Marie Curie Fellowship to LISiN, Politecnico di Torino and University of Maribor),

  • The Commission of the European Union, within Framework 7, under ERC Advanced Research Grant Agreement Number 267888, “DEMOVE” (to Georg-August University in Göttingen),

  • The Commission of the European Union, within Framework 7, under Grant Agreement Number 287739, “NeuroTREMOR” (to University of Maribor and Georg-August University in Göttingen),

  • The Commission of the European Union, within Framework 7, under Grant Agreement Number 224051, “TREMOR” (to University of Maribor, Georg-August University in Göttingen),

  • The Commission of the European Union, within Framework 7, under Marie Curie Reintegration Grant Agreement Number 239216, “iMOVE” (to University of Maribor),

  • The Institute for Scientific Interchange Foundation and Fondazione CRT, within the Lagrange Fellow 2005 project “Identification of central nervous system muscle control strategies by means of multichannel surface electromyograms decomposition” (to LISiN, Politecnico di Torino, Italy),

  • The bank foundation “Compagnia di San Paolo” of Torino, Italy, Project “Neuromuscular Investigation and Conditioning in Endocrine Myopathies” (to LISiN, Politecnico di Torino, Italy),

  • The bank foundation “Fondazione CARIPLO” of Milan, Italy, Project “Steroid myopathy: Molecular, Histopathological, and Electrophysiological Characterization”, (to University of Torino, Italy).